img1
Environment
Conservation Journal

"An International Journal Devoted to Conservation of Environment"

(A PEER REVIEWED/REFEREED JOURNAL)

ISSN: 2278-5124 (Online) :: ISSN: 0972-3099 (Print)

img2
Environment
Conservation Journal

"An International Journal Devoted to Conservation of Environment"

(A PEER REVIEWED/REFEREED JOURNAL)

ISSN: 2278-5124 (Online) :: ISSN: 0972-3099 (Print)

img3
Environment
Conservation Journal

"An International Journal Devoted to Conservation of Environment"

(A PEER REVIEWED/REFEREED JOURNAL)

ISSN: 2278-5124 (Online) :: ISSN: 0972-3099 (Print)

img4
Environment
Conservation Journal

"An International Journal Devoted to Conservation of Environment"

(A PEER REVIEWED/REFEREED JOURNAL)

ISSN: 2278-5124 (Online) :: ISSN: 0972-3099 (Print)

img5
Environment
Conservation Journal

"An International Journal Devoted to Conservation of Environment"

(A PEER REVIEWED/REFEREED JOURNAL)

ISSN: 2278-5124 (Online) :: ISSN: 0972-3099 (Print)

previous arrow
next arrow

Screening of an ethnomedicinal plant Erythrina indica Lam. for their antimicrobial, antioxidant and phytochemical properties against ear pathogens

Kaushal Aparna , Navneet, Kumar Sanjay

Department of Botany and Microbiology, Gurukul Kangri University, Haridwar-249404, Uttarakhand, India

Abstract

A significant use of plants and their products as herbal medicine is the traditionally important mode of treatment all over the world. The present work is aimed to evaluate the therapeutic potential of Erythrina indica leaves extracts. The crude extract of Erythrina indica leaves was evaluated for antimicrobial, antioxidant and phytochemical analysis against ear pathogens. E. indica crude extracts showed moderate antimicrobial activities. The Minimum inhibitory concentration 3.12 mg/ml of methanol extract was found effective against S. epidermidis and H. influenzae. The fungitoxic effects of the methanol extract on the mycelial growth of test fungi was determined which is found above 600 µg/ml. Antioxidant activity of methanol extract of Erythrina indica leaves was found lower than ascorbic acid by DPPH free radical scavenging activity. The phytochemical screening for MeOH extract of E. indica revealed the presence of phenols, flavonoids, glycosides, alkaloids, steroids and tannins. This study supports the use of Erythrina indica in herbal medicine and as a base for the development of new drugs and phytomedicine in rationale for its use in treatment of ear diseases.

Antimicrobial activity, antioxidant activity, agar well diffusion method, poisoned food technique, phytochemical screening, Minimum inhibitory concentration, 2,2-diphenyl-1-picrylhydrazyl assay

Aboaba, O.O., Smith, S.I., Olude, F.O.  2006. Antibacterial effect of edible plant extract on Escherichia coli 0157: H7. Pakistan Journal of Nutrition. 5: 325-327.

Agarwal, M. and Sarin, R. 2014. Screening of antimicrobial potential of flavonoids extracted from Erythrina indica.  International Journal of Pharma Research & Review. 3: 21-27.

Ahmed, I., Mehmood, Z., Mohammad, F. 1998.  Screening of some Indian medicinal plants for their antimicrobial properties. Journal Ethnopharmacology 62: 183-193.

Amir, F., Yam, W.S., Koay, Y.C. 2011. Phytochemical constituents and biological activities of Erythrina indica. European Journal of Chemistry. 2: 561‐565.

Aneja, K.R., Sharma, C., Joshi, R. 2012. Antimicrobial activity of Terminalia arjuna Wight & Arn.: an ethnomedicinal plant against pathogens causing ear infection. Brazilian Journal Otorhinolaryngology. 78: 68-74.

Barber, D.A. and Harris, S.R. 1994. Oxygen Free Radicals and Antioxidants: A Review: The use of antioxidant vitamin supplements to scavenge free radicals could decrease the risk of disease. American pharmacy. 34: 26-35.

Bonjar, S. 2004. Evaluation of antibacterial properties of some medicinal plants used in Iran. Journal Ethnopharmacology. 94:301–305.

Cao, G., Sofic, E., Prior, R.L. 1996. Antioxidant capacity of tea and common vegetables. Journal Agricultural Food Chemistry 44: 3426-3431.

Deattu, N., Suseela, L., Narayanan, N. 2012. Evaluation of antibacterial and antifungal activates of ethanolic polyherbal extract. Journal of Drug Delivery & Therapeutics 2: 53-55.

Dhingra, P.L. and Dhingra, S. 2014. Diseases of ear, nose and throat & head and neck surgery. 6th ed. Reed Elsevier India Pvt Ltd, New Delhi.

Evans, W.C. 2009. Trease and Evans pharmacognosy, 16th edn. Elsevier Health Sciences.

Ghosal, S., Dutta, S.K., Bhathacharya, S.K. 1972. Erythrina-chemical and pharmacological evaluation II: Alkaloids of Erythrina variegata L. Journal of Pharmaceutical Sciences. 61: 1274–1277.

Grover, R.K. and Moore, J.D. 1962. Toxicometric studies of fungicides against brown rot organisms, Sclerotonia fructicola and S. laxa. Phytopathology 52: 876-880.

Haque, R., Ali, M.S., Saha, A., Allimuzzaman, M. 2006. Analgesic activity of methanolic extract of the leaf of Erythrina variegataJournal of Pharmaceutical Sciences. 5: 77–79.

Jagessar, R.C., Mohamed, A., Gomes, G. 2008. An evaluation of the antibacterial and antifungal activity of leaf extracts of Momordica charantia against Candida albicans, Staphylococcus aureus and Escherichia coli. Nature and Science. 6: 1-14.

Jesupillai, M., Jasemine, S., Palanivelu, M. 2008. Diuretic activity of leaves of Erythrina indica Lam. International Journal of Green Pharmacy. Oct-Dec: 218-219.

Khare, C.P. 2007. Indian Medicinal Plants: An Illustrated Dictionary. Springer, New York pp 246-247.

Kumar, S., Navneet, Tiwari, M.M., Gautam, S.S. 2014. Antimicrobial and phytochemical screening of Olea europaea Linn. extracts against dental pathogens. African Journal of Microbiology Research. 8: 3373-3377.

Maobe, M.A.G., Gitu,, L., Gatebe, E., Rotich, H., Karanja, P.N., Votha, D.M., Wambugu, J., Muingai, C. 2013. Antimicrobial activities of eight selected medicinal herbs used for the treatment of diabetes, malaria and pneumonia in Kisii region, Southwest Kenya. Global Journal of Pharmacology. 7: 25-33.

Moon, K., Katolkar, P., Khadabadi, S.S. 2010. In vitro antioxidant activity of methanolic extract of Erythrina indica. Der Pharmacia Lettre. 2: 16-21.

Mujahid, Md., Siddiqui, H.H., Hussain, A., Hussain, Md. S. 2014. In- vitro evaluation of free radical scavenging activity of Erythrina indica leaves. Journal of Drug Delivery & Therapeutics 4: 49-54

Muthukrishnan, S., Palanisamy, S., Santhanam, I., Muthukrishnan, G.K. 2014. Phytochemical screening and antimicrobial activity of Erythrina variegata. World Journal of Pharmacy and Pharmaceuutical Sciences. 3: 680-690.

Nene,Y. and Thapilyal L. 2000. Poisoned food technique. Fungicides in plant disease control. 3rd Edn. Oxford and IBH Publishing Company, New Delhi.

Pandya, D.J., Yadav, E.N., Kardani, B.R., Joshi, K.K., Desai, T.R., Patel, V.L. 2012. Phytopharmacognostic study of leaves of Erythrina indica. Research Journal of Pharmaceutical Biology and Chemistry Science. 3: 127.

Proestos, C., Zoumpoulakis, P., Sinanoglou, V.J. 2013. Determination of plant bioactive compounds, antioxidant capacity and antimicrobial screening. Focusing on modern food industry. 2: 26-35.

Roland, P.S. and Stroman, D.W. 2002. Microbiology of acute otitis externa. La­rygoscope 112: 166-177.

Rosenfeld, R.M., Brown, L., Cannon, C.R., Dolor, R.J., Ganiats, T.G., Hannley, M., Kokemueller, P., Marcy, S.M., Roland, P.S., Shiffman, R.N., Stinnett, S.S., Witsell, D.L. 2006. Clinical practice guideline: acute otitis externa. Otolaryngology Head Neck Surgury. 134: 4-23.

Sakat, S.S. and Juvekar, A.R. 2010. Comparative Study of Erythrina indica Lam. (Febaceae) Leaves Extracts for Antioxidant Activity. Journal Young Pharmacology. 2: 63-67.

Scalbert, A. 1991. Antimicrobial properties of tannins. Phytochemistry. 30: 3875-3883.

Shariff, N., Sudarshana, M.S., Umesha ,S., Hariprasad, P. 2006. Antimicrobial activity of Rauvolfia tetraphylla and Physalis minima leaf and callus extracts. African Journal Biotechnology. 5: 946-950.

Somchit, M.N., Reezal, I., Nur, I.E., Mutalib, A.R. 2003. In vitro antimicrobial activity of ethanol and water extracts of Cassia alata. Journal Ethnopharmacology. 84:1–4.

Thompson, D.P. 1989. Fungitoxic activity of essential oil components on food storage fungi. Mycologia. 81(1):151-153.

Young, I.S. and Woodside, J.V. 2001. Antioxidants in health and disease. Journal Clinical Pathology. 54: 176-186.

Aparna, K., & Sanjay, K. (2018). Screening of an ethnomedicinal plant Erythrina indica Lam. for their antimicrobial, antioxidant and phytochemical properties against ear pathogens. Environment Conservation Journal19(3), 165-172.

https://doi.org/10.36953/ECJ.2018.19324

Received: 23.05.2018

Revised: 20.08.2018

Accepted: 14.11.2018

First Online: 22.12. 2018

:https://doi.org/10.36953/ECJ.2018.19324

MANUSCRIPT STATISTICS

Publisher Name:  Action for Sustainable Efficacious Development and Awareness (ASEA)

Print : 0972-3099           

Online :2278-5124